Ultrasonic Measurement of Micro-Acoustic Properties of the Biological Soft Materials
Acoustic microscopy can provide not only the morphology, but also the biomechanical properties of biological soft tissues. Especially, the biomechanics of myocardial infarction and atherosclerosis is important because the pathophysiology of those diseases is closely related to mechanical properties and to mechanical stress. Two types of Scanning Acoustic Microscope (SAM), operating in 100 to 200 MHz and in 800 MHz to 1.3 GHz frequency ranges were equipped to measure the acoustic properties of biological soft tissues. The values of attenuation and sound speed in the tissue components of atherosclerosis were measured by analyzing the frequency dependent characteristics of the amplitude and phase of the ultrasonic signals. The SAM has shown that it is possible to asses the biomechanics of the tissues and that it might improve our understanding of diseases from a micro-mechanical point of view.
Ultrasound, Acoustic Microscopy, Gastric Cancer, Renal Cancer, Myocardial Infarction, Atherosclerosis, Collagen, Cell.